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One class of azacalixpyridines, shown in Table 1 and [ FIGURE 1 ] as compound 1, has been synthesized through an S(N)2-addition of acyl azide to 2-bromo-4,4,6,6,7,8,8,9-octahydro-3H-carbazole.
Other azacalixpyridines, shown in Table 1 and [ FIGURE 1 ] as compounds 2-5, have been synthesized through azide-alkyne cycloaddition reactions using compounds 1 as a substrate.
The synthesis of 1, 4 and 7 was carried out as described in Table 1. Compounds 1-7 were tested for HIV-1 fusion inhibitory activity in an in vitro HIV-1 fusion assay described in Table 1.This ad is presented by Loyalty 360, a provider of membership solutions for organizations, brands and retailers.
The views and opinions expressed in this article are those of the author and do not necessarily reflect the official policy or position of CBS Local.com.
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On Monday, August 5, President Donald Trump signed the Tax Cuts and Jobs Act into law.
As a result of this tax cut, more money is going to the top one percent, rather than the average American.
Bernie Sanders tweeted that people should not wait to strike, and we at CBS Local agree.
Here is a list of items to buy that won’t be taxed by this bill.
Tesla and Apple
The average price of a new car is $34,000, while the average price of a used car is $13,000.
To put these numbers into perspective, the Chevy Volt is $11,000.
Tesla and Apple are two companies that sell a lot of cars.
And if the final bill is enacted, those two companies could see a huge bump in profits.
Don’t get me wrong; I think electric cars are the future and I like the idea of a personal transportation network, but I do not believe that the government should be subsidizing any particular company.
Rather than passing the “car” tax onto consumers, the money should go towards making all roads in America a little bit safer.
Democrats and Republicans, will you please get in a room and come to an agreement?
Your health
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